Lorazepam vs Diazepam for Pediatric Status Epilepticus
نویسندگان
چکیده
منابع مشابه
Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.
IMPORTANCE Benzodiazepines are considered first-line therapy for pediatric status epilepticus. Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. OBJECTIVE To test the hypothesis that lorazepam has better efficacy and safety than diazepam for treating pediatric status epilepticus. ...
متن کاملA comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus.
BACKGROUND It is uncertain whether the administration of benzodiazepines by paramedics is an effective and safe treatment for out-of-hospital status epilepticus. METHODS We conducted a randomized, double-blind trial to evaluate intravenous benzodiazepines administered by paramedics for the treatment of out-of-hospital status epilepticus. Adults with prolonged (lasting five minutes or more) or...
متن کاملA comparison of lorazepam and diazepam as initial therapy in convulsive status epilepticus.
BACKGROUND Previous trials have suggested lorazepam may be superior to diazepam as first-line treatment of convulsive status epilepticus (CSE), with improved seizure outcome, and a lower incidence of side-effects. Many published guidelines however still recommend diazepam. AIM To compare the efficacy, safety and cost of lorazepam compared to diazepam, in adults with CSE. DESIGN Retrospectiv...
متن کاملReview: lorazepam provides the best control for status epilepticus.
and commentary also appear in ACP Journal Club and a modified version of the abstract appears in Evidence-Based Nursing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Dr K Prasad, All India Institute of Medical Sciences, New Delhi, India. [email protected] Source of funding: no external f...
متن کاملPharmacokinetics of intravenous lorazepam in pediatric patients with and without status epilepticus.
OBJECTIVE To evaluate the single dose pharmacokinetics of an intravenous dose of lorazepam in pediatric patients treated for status epilepticus (SE) or with a history of SE. STUDY DESIGN Ten hospitals in the Pediatric Emergency Care Applied Research Network enlisted patients 3 months to 17 years with convulsive SE (status cohort) or for a traditional pharmacokinetics study (elective cohort). ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: JAMA
سال: 2014
ISSN: 0098-7484
DOI: 10.1001/jama.2014.2625